10-5 Blood and hematopoiesis

BLOOD CELLS

Neutrophils – 1

Observe the nucleated cell at the center of the upper figure. It is slightly larger than the red blood cells that surround it.
Hover your cursor or click on the image to differentiate its nucleus and cytoplasm.
Its nucleus has dense chromatin: it is quite stained and has dark clumps of chromatin. What is most striking is the fact that it has four small segments joined by thin filaments of chromatin.
Its cytoplasm has larger granules stained in a color similar to that of the cytoplasm: they are grains of neutral coloration – neither red nor blue. They are called Specific granules.
It is, therefore, a segmented neutrophil surrounded by red blood cells.
Neutrophils have in their cytoplasm other types of granules such as the Azurophilic granules and the tertiary granules. The Azurophylic ones are lysosomes and are very small and stain in purple, but not always seen in smears.

Blood smear. Staining: Leishman. Large magnification.

The cell shown in the lower image has the same features.

Blood smear. Staining: Leishman. Large magnification.

Blood smear. Staining: Leishman. Large magnification.

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