EPIPHYSEAL DISK – 7
The upper image shows the transition between the calcified cartilage zone and the epiphyseal disc ossification zone. A line indicates the boundary between the two zones.
The region above the line is calcified cartilage. Below the line, it is easy to see that there is other tissue: bone tissue that has been deposited on the calcified cartilage septa.
The lower image is a higher magnification of this transition site.
In the final region of the calcified cartilage zone, the chondrocytes have undergone a process of cell death, and their nuclei and cytoplasm have disintegrated.
Many sites previously occupied by chondrocytes now appear empty. These are spaces previously occupied by chondrocytes (highlighted in green).
In the lower part of the image: the walls of extracellular matrix that contained cartilage cells is covered by a thin layer of bone tissue (osteoblasts, osteocytes and bone extracellular matrix).
The region above the line is calcified cartilage. Below the line, it is easy to see that there is other tissue: bone tissue that has been deposited on the calcified cartilage septa.
The lower image is a higher magnification of this transition site.
In the final region of the calcified cartilage zone, the chondrocytes have undergone a process of cell death, and their nuclei and cytoplasm have disintegrated.
Many sites previously occupied by chondrocytes now appear empty. These are spaces previously occupied by chondrocytes (highlighted in green).
In the lower part of the image: the walls of extracellular matrix that contained cartilage cells is covered by a thin layer of bone tissue (osteoblasts, osteocytes and bone extracellular matrix).
Epiphyseal disc. Staining: HE. Magnification: small.
Epiphyseal disc.