1-18 Basic concepts

THINKING ON 3-DIMENSIONS – 6
Cells lacking a nucleus and nuclei lacking nucleoli

The image is of a section of the cerebellum, an organ that belongs to the central nervous system, located inside the skull under the brain.
In addition to several smaller neurons, observe three large neurons of a type called Purkinje cells.
1 – Firstly watch their nuclei and nucleoli.
2 – Place the cursor or click on the image:
Purkinje cells 1 and 3 – have unprecise nuclei and no obvious nucleoli.
Purkinje cell 2 – shows an evident nucleus and nucleolus.
Cells “lacking” nuclei, or nuclei without nucleoli are often seen in sections of most organs.
Why do cells show such varied appearances? See next page for an explanation.



Cerebellum. Hematoxylin and eosin. Medium magnification.

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