INTRAMEMBRANOUS OSSIFICATION – 1
A good example of intramembranous ossification is found in the histogenesis of flat bones of the skull, that occurs within a mesenchymal membrane .
The figure shows nuclei of cells of the mesenchymal membrane placed under the skull skin of a laboratory animal fetus (highlighted in orange). Most nuclei belong to mesenchymal cells.
A condensation of nuclei can be seen in a region highlighted in green. This type of condensation typically indicates that groups of cells are undergoing a differentiation event to develop into tissues and organs.
Skull of a fetal mouse. Staining: HE. Magnification: small.
