TRANSIENT CELLS OF THE CONNECTIVE TISSUE – 2
INFLAMMATORY INFILTRATE
The connective tissue is the main site of inflammatory reactions in the body.
The amount of transient connective tissue cells increases significantly in sites of the body undergoing a local inflammation. Chemical signals emitted by dead microorganisms and by dead cells attract leukocytes, macrophages and plasma cells that result in an inflammatory infiltrate, often accompannied by local edema and pain.
The types of cells present in an inflammatory infiltrate vary greatly, depending mainly on:
– The agent that stimulated the reaction. The cell population can be very different depending on whether the reaction is against a bacterium, a protozoan, or a physical agent (e.g., heat radiation, i.e., a burn).
2 – The timing of its analysis. For example, a bacterial infection ensues a fast, acute response consisting primarily of neutrophils and probably macrophages and perhaps eosinophils. On a later stages these cells may disappear and lymphocytes and plasma cells appear and may persist for variable periods of time.
The image shows an inflammatory infiltrate (highlighted in pink) in an area of connective tissue beneath a stratified squamous epithelium.
The amount of transient connective tissue cells increases significantly in sites of the body undergoing a local inflammation. Chemical signals emitted by dead microorganisms and by dead cells attract leukocytes, macrophages and plasma cells that result in an inflammatory infiltrate, often accompannied by local edema and pain.
The types of cells present in an inflammatory infiltrate vary greatly, depending mainly on:
– The agent that stimulated the reaction. The cell population can be very different depending on whether the reaction is against a bacterium, a protozoan, or a physical agent (e.g., heat radiation, i.e., a burn).
2 – The timing of its analysis. For example, a bacterial infection ensues a fast, acute response consisting primarily of neutrophils and probably macrophages and perhaps eosinophils. On a later stages these cells may disappear and lymphocytes and plasma cells appear and may persist for variable periods of time.
The image shows an inflammatory infiltrate (highlighted in pink) in an area of connective tissue beneath a stratified squamous epithelium.
Inflammatory infiltrate. Staining: HE. Magnification: low.
