RESIDENT CELLS OF THE CONNECTIVE TISSUE
FIBROBLAST – 1
FIBROBLAST – 1
The type of connective tissue that has been analyzed so far in this chapter is the most common type of non-specialized connective tissue of the body, called connective tissue proper. It is found in the skin and inside and around most organs.
The most common cells of this tissue are the fibroblasts.
They are the majority of cells observed in the image. Fibroblasts are elongated, placed between the collagen fibers and have elongated nuclei. Their cytoplasm is often very thin. After hematoxylin and eosin staining it stains as the collagen fibers and may not be always noticed.
They are very important for the functioning of the connective tissue, as they synthesize and secrete a large portion of its extracellular matrix. As they also digest and reabsorb the matrix, they control its amount and quality following signals emitted locally or originated elsewhere in the body.
Distinguish two main components of the image:
1 – collagen fibers, stained pink by eosin. They vary in size, thickness and directions.
2 – Fibroblasts, placed between the collagen fibers, can be recognized by the elongated nuclei.
The most common cells of this tissue are the fibroblasts.
They are the majority of cells observed in the image. Fibroblasts are elongated, placed between the collagen fibers and have elongated nuclei. Their cytoplasm is often very thin. After hematoxylin and eosin staining it stains as the collagen fibers and may not be always noticed.
They are very important for the functioning of the connective tissue, as they synthesize and secrete a large portion of its extracellular matrix. As they also digest and reabsorb the matrix, they control its amount and quality following signals emitted locally or originated elsewhere in the body.
Distinguish two main components of the image:
1 – collagen fibers, stained pink by eosin. They vary in size, thickness and directions.
2 – Fibroblasts, placed between the collagen fibers, can be recognized by the elongated nuclei.
Connective tissue proper. Staining: HE. Small magnification.