4-13 Connective tissue

RETICULAR FIBERS – 2
The spleen is rich in reticular fibers.
They can be distinguished in light microscopy after treatment of sections with the periodic acid-Schiff (PAS) technique.
The spleen has an extensive set of blood capillaries with dilated and irregular lumens, called sinusoids (that exist also in some other organs).
In the spleen and other sites the sinusoids are supported by a net of reticular fibers that surround their walls, as if they were the arches that surround a wooden barrel, holding the the wall structure together.
When you hover your cursor over or click on the image some of the fibers that surround two sinusoids become highlighted in light-blue to show their arrangement. The sinusoid lumen is highlighted in pink.

Spleen. Staining: Periodic acid-Schiff (PAS). Magnification: medium.


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