{"id":6124,"date":"2018-03-15T12:26:27","date_gmt":"2018-03-15T15:26:27","guid":{"rendered":"http:\/\/en-mol.icb.usp.br\/?page_id=6124"},"modified":"2026-03-22T13:21:46","modified_gmt":"2026-03-22T16:21:46","slug":"1-4-basic-concepts","status":"publish","type":"page","link":"https:\/\/mol-en.icb.usp.br\/index.php\/1-4-basic-concepts\/","title":{"rendered":"1-4 Basic concepts"},"content":{"rendered":"<div class=\"su-row\">\n<div class=\"su-column su-column-size-1-1\"><div class=\"su-column-inner su-u-clearfix su-u-trim\"> <strong>NUCLEUS AND CYTOPLASM<\/strong> <\/div><\/div>\n<\/div>\n<div class=\"su-row\">\n<div class=\"su-column su-column-size-1-2\"><div class=\"su-column-inner su-u-clearfix su-u-trim\">\nThis image is higher magnification view of a liver section.<br \/>\nThe majority of the liver cells are epithelial cells called <strong>hepatocytes<\/strong>. Blue or purple circles seen inside their cytoplasm are the nuclei of the hepatocytes. Inside many of them observe a strongly stained round structure, the nucleolus.<br \/>\n<strong>Hematoxylin<\/strong> and <strong> eosin <\/strong>are the stains the were used to stain this histological section. The nuclei appear blue\/purple with hematoxylin and the cytoplasm\u00a0pink\/orange with eosin. This is the most commonly stain combination used to observe histological sections. In the final part of this chapter you can find more informations on staining histological sections.<br \/>\nThe hepatocytes seem to form columns or cords. Actually, however, the liver hepatocytes are organized as three-dimensional plates. Later in this chapter you will realize that thin sections of three-dimensional structures need to be properly interpreted, in order to understand the true arrangement of their cells as they form tissues and organs.<br \/>\nBlood passes inside the spaces that exist between the plates of hepatocytes, but in this section they appear empty as a result of the procedute used to produce the section.<br \/>\nTo find out the sizes of structures of this image, use the bar placed at the lower right corner of the figure, which measures measures 20 \u03bcm.<\/p>\n<p><strong>Below the image observe the figure of a hand holding a mouse. This means that a special effect caused by the position of the mouse cursor will help you to recognize some structures of this organ.<br \/>\nPlacing the mouse cursor over the image or clicking on the image will distinguish the cytoplasm &#8211; in pink &#8211; and the nuclei in blue.<\/strong><\/p>\n<div>\n<div class=\"image-container\">\n<div class=\"extra\">\n<a href=\"javascript:void(0)\"><br \/>\n  <img decoding=\"async\" src=\"https:\/\/mol-en.icb.usp.br\/wp-content\/uploads\/1-4.jpg\"\n       class=\"hover-image\"\n       data-original-src=\"https:\/\/mol-en.icb.usp.br\/wp-content\/uploads\/1-4.jpg\"\n       data-hover-src=\"https:\/\/mol-en.icb.usp.br\/wp-content\/uploads\/1-4MOB.jpg\" \/><br \/>\n<\/a><\/p>\n<p>Liver. Hematoxylin and eosin. Medium magnification.<\/p>\n<p><img decoding=\"async\" src=\"http:\/\/mol.icb.usp.br\/wp-content\/uploads\/mouse-1.gif\" \/><\/p>\n<p>\n<strong>Desktops and notebooks<\/strong>: Place the cursor over the figure to access another image.<br \/>\n<strong>Touchscreens<\/strong>: Click on the figure to access another image. Click outside of the figure to return to the first image.<\/p>\n<p><a href=\"https:\/\/mol-en.icb.usp.br\/index.php\/1-5-basic-concepts\/\">NEXT PAGE<\/a><\/p>\n<p><a href=\"https:\/\/mol-en.icb.usp.br\/index.php\/1-3-basic-concepts\/\">PREVIOUS PAGE<\/a><\/p>\n<p><a href=\"https:\/\/mol-en.icb.usp.br\/index.php\/1-0-basic-concepts\/\">MENU OF THIS CHAPTER<\/a><br \/>\n&nbsp;<\/p>\n<\/div><\/div>\n<div class=\"su-column su-column-size-1-2\"><div class=\"su-column-inner su-u-clearfix su-u-trim\">\n<\/div>\n<\/div>\n<\/div><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-6124","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages\/6124","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/comments?post=6124"}],"version-history":[{"count":73,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages\/6124\/revisions"}],"predecessor-version":[{"id":21121,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages\/6124\/revisions\/21121"}],"wp:attachment":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/media?parent=6124"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}