{"id":3285,"date":"2017-11-17T15:52:47","date_gmt":"2017-11-17T17:52:47","guid":{"rendered":"http:\/\/en-mol.icb.usp.br\/?page_id=3285"},"modified":"2026-07-13T21:57:57","modified_gmt":"2026-07-14T00:57:57","slug":"7-18-bone","status":"publish","type":"page","link":"https:\/\/mol-en.icb.usp.br\/index.php\/7-18-bone\/","title":{"rendered":"7-18 Bone"},"content":{"rendered":"
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ARRANGEMENT OF LAMELLAR BONE IN THE DIAPHYSES \u2013 3<\/strong> <\/div><\/div>\n<\/div>\n
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The wall of the diaphysis of mature bones is formed by thousands or millions of very thin bone plates, the bone lamellae<\/strong>. They are made of calcified collagen fibers plus other components of extracellular matrix. Osteocytes are placed between the lamellae.
\nThe wall is composed by three layers of lamellae.
\n1 – The external or outer circumferential lamellae<\/strong> (highlighted in red) surround the diaphysis as several layers of stacks of curved parallel lamellae.
\n2 – The thin inner border of the diaphysis, facing the medullary canal, is composed by internal or inner circumferential lamellae<\/strong>, stacks of curved parallel lamellae (highlighted in green).
\n3 – The widest layer is the middle one (highlighted in blue). It contains Haversian systems<\/strong> and interstitial lamellae<\/strong>, stacks of differently sized lamellae placed between Haversian systems.<\/p>\n

Excepting the articular surfaces, all internal and external surfaces of bones are covered by cell layers called respectively endosteum<\/strong> and periosteum<\/strong> (not visible in the figure). These layers are formed by bone lining cells (osteoprogenitors plus active and inactive osteoblasts).
\nThe endosteum, usually a thin layer, stays in direct contact with the content of medullary cavity. The thicker periosteum is made of connective tissue proper placed over the osteoprogenitors and osteoblasts. <\/p>\n<\/div><\/div>\n

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Layers of lamellae of a diaphysis.<\/p\n\nCross-section of part of the wall of a diaphysis. Schmorl's technique. Small magnification:.<\/p>\n

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