{"id":3036,"date":"2017-10-28T11:26:30","date_gmt":"2017-10-28T13:26:30","guid":{"rendered":"http:\/\/en-mol.icb.usp.br\/?page_id=3036"},"modified":"2026-03-18T18:17:20","modified_gmt":"2026-03-18T21:17:20","slug":"6-5-cartilage","status":"publish","type":"page","link":"https:\/\/mol-en.icb.usp.br\/index.php\/6-5-cartilage\/","title":{"rendered":"6-5 Cartilage"},"content":{"rendered":"<div class=\"su-row\">\n<div class=\"su-column su-column-size-1-1\"><div class=\"su-column-inner su-u-clearfix su-u-trim\"> <strong>HYALINE CARTILAGE &#8211; 3<\/strong> <\/div><\/div>\n<\/div>\n<div class=\"su-row\">\n<div class=\"su-column su-column-size-1-2\"><div class=\"su-column-inner su-u-clearfix su-u-trim\">\n<p><strong> GROWTH OF CARTILAGE. ISOGENOUS GROUPS.<\/strong>. <\/p>\n<p>Sections of a mature hyaline cartilage show that most of its chondrocytes are not isolated. Very often they appear as agregates called <strong>isogenous groups<\/strong>. Each group is separated from neighbour groups by ECM.<br \/>\nThe isogenous groups of chondrocytes result from one of the ways of growth of cartilage pieces called <strong>interstitial growth<\/strong>. Chondrocytes placed inside the cartilage divide by mitosis and due to the semi-rigid consistency of the extracellular matrix, their daughter cells tend to remain close. A few cycles of division of one chondrocyte result in the production of a small tri-dimensional cell aggregate, an isogenous group. Each one contains a clone of chondrocytes.<br \/>\nAnother type of cartilage growth is called <strong>appositional growth<\/strong>. It happens by the addition new chondrocytes at the external surface of cartilage piece. New chondrocytes originate from the differentiation of mesenchymal cells present in the cartilage perichondrium.<br \/>\nBoth types of growth may happen simultaneously in the same cartilage piece.<br \/>\nThree isogenic groups are indicated in the image.<\/p>\n<\/div><\/div>\n<div class=\"su-column su-column-size-1-2\"><div class=\"su-column-inner su-u-clearfix su-u-trim\">\n<p><img decoding=\"async\" src=\" https:\/\/mol-en.icb.usp.br\/wp-content\/uploads\/6-5-IG.jpg \" \/><\/a><\/p>\n<p>Trachea. Staining: HE. Medium magnification.<\/p>\n<p><img decoding=\"async\" src=\"http:\/\/mol.icb.usp.br\/wp-content\/uploads\/mouse-1.gif\"\/><\/a><\/p>\n<p><strong><br \/>\n<a href=\"https:\/\/mol-en.icb.usp.br\/index.php\/6-6-cartilage\/\">NEXT PAGE<\/a><\/p>\n<p><a href=\"https:\/\/mol-en.icb.usp.br\/index.php\/6-4-cartilage\/\">PREVIOUS PAGE<\/a><\/p>\n<p><a href= https:\/\/mol-en.icb.usp.br\/index.php\/6-0-cartilage\/\">MENU OF THIS CHAPTER<\/a><\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-3036","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages\/3036","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/comments?post=3036"}],"version-history":[{"count":49,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages\/3036\/revisions"}],"predecessor-version":[{"id":20990,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages\/3036\/revisions\/20990"}],"wp:attachment":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/media?parent=3036"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}