{"id":2723,"date":"2017-09-18T15:04:54","date_gmt":"2017-09-18T18:04:54","guid":{"rendered":"http:\/\/en-mol.icb.usp.br\/?page_id=2723"},"modified":"2026-03-14T21:06:34","modified_gmt":"2026-03-15T00:06:34","slug":"4-18-connective-tissue","status":"publish","type":"page","link":"https:\/\/mol-en.icb.usp.br\/index.php\/4-18-connective-tissue\/","title":{"rendered":"4-18 Connective tissue"},"content":{"rendered":"<div class=\"su-row\">\n<div class=\"su-column su-column-size-1-1\"><div class=\"su-column-inner su-u-clearfix su-u-trim\"> <strong>RESIDENT CELLS OF THE CONNECTIVE TISSUE<\/p>\n<p>MAST CELL<br \/>\n<\/strong><\/div><\/div>\n<\/div>\n<div class=\"su-row\">\n<div class=\"su-column su-column-size-1-2\"><div class=\"su-column-inner su-u-clearfix su-u-trim\">\nThe mast cells are large, round or oval-shaped and often found close to blood vessels.<br \/>\nThey participate in inflammatory and allergic reactions by secreting several molecules, such as histamine and heparin, that are accumulated in cytoplasmic vacuoles also called granules.<br \/>\nTheir nucleus is usually centrally positioned and many granules can be seen in the cytoplasm.<br \/>\nThe granules are usually not well stained by hematoxylin and eosin and for this reason the mast cells are not easily recognized in sections stained with these stains. On the other hand, they stain very well with metachromatic dyes, such as toluidine blue and also by stains for elastic tissue, such as Weigert&#8217;s stain.<br \/>\nMetachromatic dyes are so called because they stain cellular structures in a color slightly different from their original color. Mast cell granules, for example, stain purple instead of blue by toluidine blue.<br \/>\nThe image is of a whole-mount preparation of a small piece of a mesentery that was stained to demonstrate elastic fibers. The mast cell nucleus is not stained, but its cytoplasm is filled with granules.<br \/>\nThe thin fibrils are elastic fibers of the extracellular matrix.<\/p>\n<\/div><\/div>\n<div class=\"su-column su-column-size-1-2\"><div class=\"su-column-inner su-u-clearfix su-u-trim\">\n<img decoding=\"async\" src=\" https:\/\/mol-en.icb.usp.br\/wp-content\/uploads\/4-18B.jpg \" \/><\/a><\/p>\n<p>Whole mount of mesentery. Staining: Weigert. Large magnification.<\/p>\n<p><strong><br \/>\n<a href=https:\/\/mol-en.icb.usp.br\/index.php\/4-19-connective-tissue\/\">NEXT PAGE<\/a><\/p>\n<p><a href=https:\/\/mol-en.icb.usp.br\/index.php\/4-17-connective-tissue\/\">PREVIOUS PAGE<\/a><\/p>\n<p><a href= https:\/\/mol-en.icb.usp.br\/index.php\/4-0-connective-tissue\/\">MENU OF THIS CHAPTER<\/a><\/p>\n<\/div><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-2723","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages\/2723","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/comments?post=2723"}],"version-history":[{"count":47,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages\/2723\/revisions"}],"predecessor-version":[{"id":20895,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages\/2723\/revisions\/20895"}],"wp:attachment":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/media?parent=2723"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}