{"id":15081,"date":"2025-10-05T18:06:26","date_gmt":"2025-10-05T21:06:26","guid":{"rendered":"https:\/\/mol-en.icb.usp.br\/?page_id=15081"},"modified":"2026-05-11T22:33:47","modified_gmt":"2026-05-12T01:33:47","slug":"7-7-bone","status":"publish","type":"page","link":"https:\/\/mol-en.icb.usp.br\/index.php\/7-7-bone\/","title":{"rendered":"7-7 Bone"},"content":{"rendered":"<div class=\"su-row\">\n<div class=\"su-column su-column-size-1-1\"><div class=\"su-column-inner su-u-clearfix su-u-trim\"><strong>CELLS OF THE BONE TISSUE &#8211; 5<\/strong> <\/div><\/div>\n<\/div>\n<div class=\"su-row\">\n<div class=\"su-column su-column-size-1-2\"><div class=\"su-column-inner su-u-clearfix su-u-trim\">\n<strong> Cell processes of osteocytes<\/strong><\/p>\n<p>Osteocytes have numerous cell processes but they are not seen in regular routine sections stained with hematoxylin and eosin and observed with a light microscope.<br \/>\nThe cell bodies of osteocytes occupy the small cavities of the matrix called <strong>lacunae<\/strong> and their extensions occupy thin tunnels that originate in the lacunae, called <strong>canaliculi<\/strong> (plural of canaliculus).<br \/>\nThe end portion of the canaliculi connect with neighbor canaliculi. Therefore the osteocytes communicate with each other and form an extensive net inside the bone matrix. This net is very important for the bone metabolism, as its extracellular matrix is not permeable to the transit of gases and liquids. Nutrients, gases and many molecules are conducted inside the canaliculi.<\/p>\n<p>The figure is of a small bone specimen specially prepared to demonstrate bone lacunae and canaliculi. The specimen was placed in a solution of the dye Thionine that difused into the spaces of the osteocytes and of their processes.<br \/>\nWhat is seen in the image is the dye inside the lacunae inhabited by osteocyte cell bodies (larger arrows) and the <strong>canaliculi<\/strong> occupied by extensions of osteocytes (smaller arrows).<br \/>\n<\/div><\/div>\n<div class=\"su-column su-column-size-1-2\"><div class=\"su-column-inner su-u-clearfix su-u-trim\">\n<p><img decoding=\"async\" src=\" https:\/\/mol-en.icb.usp.br\/wp-content\/uploads\/7-7.jpg \" \/><\/p>\n<p>Section of a bone specimen that had been placed in thionine solution. Medium magnification.<\/p>\n<\/p>\n<p><a href=\"https:\/\/mol-en.icb.usp.br\/index.php\/7-8-bone\/\">NEXT PAGE<\/a><\/p>\n<p><a href=\"https:\/\/mol-en.icb.usp.br\/index.php\/7-6-bone\/\">PREVIOUS PAGE<\/a><\/p>\n<p><a href=\"https:\/\/mol-en.icb.usp.br\/index.php\/7-0-bone\/\">MENU OF THIS CHAPTER<\/a\n\n\n<\/p>\n<\/div><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-15081","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages\/15081","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/comments?post=15081"}],"version-history":[{"count":65,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages\/15081\/revisions"}],"predecessor-version":[{"id":22392,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages\/15081\/revisions\/22392"}],"wp:attachment":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/media?parent=15081"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}