{"id":15045,"date":"2025-10-05T11:13:58","date_gmt":"2025-10-05T14:13:58","guid":{"rendered":"https:\/\/mol-en.icb.usp.br\/?page_id=15045"},"modified":"2026-05-11T22:28:02","modified_gmt":"2026-05-12T01:28:02","slug":"7-6-bone","status":"publish","type":"page","link":"https:\/\/mol-en.icb.usp.br\/index.php\/7-6-bone\/","title":{"rendered":"7-6 Bone"},"content":{"rendered":"<div class=\"su-row\">\n  <div class=\"su-column su-column-size-1-1\"><div class=\"su-column-inner su-u-clearfix su-u-trim\"> <strong>CELLS OF THE BONE TISSUE \u2013 4<\/strong> <\/div><\/div>\n<\/div>\n<div class=\"su-row\">\n  <div class=\"su-column su-column-size-1-2\"><div class=\"su-column-inner su-u-clearfix su-u-trim\">\nOsteoclasts<br \/>\nLarge multinucleated cells involved in bone tissue resorption.<br \/>\nTheir cytoplasm is usually strongly stained in red by a mixture of hematoxylin and eosin.<br \/>\nAt the interface between an osteoclast and the bone surface it is often possible to observe a thin, slightly concave space called <strong>Howship&#8217;s lacuna<\/strong>, highlighted in light brown and indicated by an arrow in the upper figure. Observe cytoplasmic extensions of the osteoclast that protrude into this space.<br \/>\nThe osteoclast cytoplasm is highlighted in light blue and its nuclei in dark blue.<br \/>\nIn the lower image: three osteoclasts, an osteocyte inside the matrix highlighted in green.<br \/>\nOsteoblasts on the surface of the bone matrix highlighted in light brown.<br \/>\n<\/div><\/div>\n<div class=\"su-column su-column-size-1-2\"><div class=\"su-column-inner su-u-clearfix su-u-trim\">\n<div onclick>\n<div class=\"image-container\">\n<div class=\"extra\">\n<div class=\"extra\">\n<a href=\"javascript:void(0)\"><img decoding=\"async\" src=\" https:\/\/mol-en.icb.usp.br\/wp-content\/uploads\/7-6-A-en.jpg \" onmouseover=\"this.src=' https:\/\/mol-en.icb.usp.br\/wp-content\/uploads\/7-6-A-MO-en.jpg'\" onmouseout=\"this.src=' https:\/\/mol-en.icb.usp.br\/wp-content\/uploads\/7-6-A-en.jpg'\" \/><\/a><\/div>\n<p>Bone trabecula. Staining: HE. High magnification.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/mol-en.icb.usp.br\/wp-content\/uploads\/mouse-1.gif\"\/><\/a><\/p>\n<p><a href=\"javascript:void(0)\"><img decoding=\"async\" src=\" https:\/\/mol-en.icb.usp.br\/wp-content\/uploads\/7-6-B-en.jpg \" onmouseover=\"this.src=' https:\/\/mol-en.icb.usp.br\/wp-content\/uploads\/7-6-B-MO-en.jpg'\" onmouseout=\"this.src=' https:\/\/mol-en.icb.usp.br\/wp-content\/uploads\/7-6-B-en.jpg'\" \/><\/a><\/div>\n<p>Bone trabecula. Staining: HE. High magnification.<\/p>\n<p><a href=\"https:\/\/mol-en.icb.usp.br\/index.php\/7-7-bone\/\">NEXT PAGE<\/a><\/p>\n<p><a href=\"https:\/\/mol-en.icb.usp.br\/index.php\/7-5-bone\/\">PREVIOUS PAGE<\/a><\/p>\n<p><a href=\"https:\/\/mol-en.icb.usp.br\/index.php\/7-0-bone\/\">MENU OF THIS CHAPTER<\/a\n\n<\/div>\n<\/div>\n<\/div>\n<p><\/body><br \/>\n<\/html> <\/div><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-15045","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages\/15045","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/comments?post=15045"}],"version-history":[{"count":64,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages\/15045\/revisions"}],"predecessor-version":[{"id":22389,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages\/15045\/revisions\/22389"}],"wp:attachment":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/media?parent=15045"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}