{"id":14030,"date":"2025-09-03T05:53:57","date_gmt":"2025-09-03T08:53:57","guid":{"rendered":"https:\/\/mol-en.icb.usp.br\/?page_id=14030"},"modified":"2026-03-14T21:10:22","modified_gmt":"2026-03-15T00:10:22","slug":"4-25-connective-tissue","status":"publish","type":"page","link":"https:\/\/mol-en.icb.usp.br\/index.php\/4-25-connective-tissue\/","title":{"rendered":"4-25 Connective tissue"},"content":{"rendered":"<div class=\"su-row\">\n  <div class=\"su-column su-column-size-1-1\"><div class=\"su-column-inner su-u-clearfix su-u-trim\"> <strong>TRANSIENT CELLS OF THE CONNECTIVE TISSUE &#8211; 4<\/strong> <\/div><\/div>\n<\/div>\n<div class=\"su-row\">\n  <div class=\"su-column su-column-size-1-2\"><div class=\"su-column-inner su-u-clearfix su-u-trim\"> <strong>Plasma cells<\/strong><\/p>\n<p>The plasma cells or plasmocytes develop from some types of B-lymphocytes, folowing antigen recognition by the lymphocytes.<br \/>\nThey are spherical or ovoid, whose cytoplasm stains with a mixture of hematoxylin and eosin due to the presence of a large amount of ribosomes in their well developed rough endoplasmic reticulum. They actively synthesize and secrete large amounts of proteins most of which are different classes of immunoglobulins (antibodies).<br \/>\nTheir nuclei are spherical, usually displaced off the cell center. They usually contain large clumps of heavily stained chromatin, some of them often placed at the nuclear periphery, under the nuclear membrane.<br \/>\nWith a light microscope, another very often feature seen around the nuclei is a clear, non-stained, halo or  area similar to a crescent moon. It is the region of the greatly developed Golgi apparatus of these cells highly involved in protein synthesis. The Golgi area does not stain well by the dyes commonly used in tissue sections. <\/p>\n<p>After clicking or hovering over the image the cytoplasm of some plasma cells becomes highlighted in red, a crescent of plasmocyte (labelled by an arrow) in the upper figure in highlighted in blue.<br \/>\n and lymphocytes in green.<br \/>\nIdentify unlabelled plasma cells in the figure.<br \/>\nPlasma cells and lymphocytes can also be seen on page <a href=\"https:\/\/mol-en.icb.usp.br\/index.php\/12-14-orgaos-linfoides\/\" rel=\"noopener\" target=\"_blank\">12-14<\/a> and in thenext pages.<br \/>\n<\/div><\/div>\n  <div class=\"su-column su-column-size-1-2\"><div class=\"su-column-inner su-u-clearfix su-u-trim\"> <\/p>\n<div onclick>\n<div class=\"image-container\">\n<div class=\"extra\">\n<a href=\"javascript:void(0)\"><img decoding=\"async\" src=\" https:\/\/mol-en.icb.usp.br\/wp-content\/uploads\/4-25-new.jpg \" onmouseover=\"this.src=' https:\/\/mol-en.icb.usp.br\/wp-content\/uploads\/4-25MO.jpg'\" onmouseout=\"this.src=' https:\/\/mol-en.icb.usp.br\/wp-content\/uploads\/4-25-new.jpg'\" \/><\/a><\/div>\n<p>Inflammatory infiltrate. Staining: HE. Magnification: medium.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/mol-en.icb.usp.br\/wp-content\/uploads\/mouse-1.gif\"\/><\/a><br \/>\n<strong><br \/>\n <a href=\"https:\/\/mol-en.icb.usp.br\/index.php\/4-26-connective-tissue\/\">NEXT PAGE<\/a><\/p>\n<p><a href=\"https:\/\/mol-en.icb.usp.br\/index.php\/4-24-connective-tissue\/\">PREVIOUS PAGE<\/a><\/p>\n<p><a href= https:\/\/mol-en.icb.usp.br\/index.php\/4-0-connective-tissue\/\">MENU OF THIS CHAPTER<\/a>\n<\/div>\n<\/div>\n<\/div>\n<p><\/body><br \/>\n<\/html> <\/div><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-14030","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages\/14030","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/comments?post=14030"}],"version-history":[{"count":58,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages\/14030\/revisions"}],"predecessor-version":[{"id":20900,"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/pages\/14030\/revisions\/20900"}],"wp:attachment":[{"href":"https:\/\/mol-en.icb.usp.br\/index.php\/wp-json\/wp\/v2\/media?parent=14030"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}